A @destination is the @I2P@in-net address of the final endpoint you are trying to connect to (example: an @I2P website, service, or Monero node). This can also include a *local destination* of which *other* peers need to connect to in order to make contact for communication (similar to how, in @clearnet, your IP address is given to a website when you connect so it knows *where* to send the information back to).
An @I2P destination can be encoded into a @base32-address or @base64-address. Most users will only care about @base32-addresses or a `.i2p` hostname while, internally, @Kovri / @I2P@address-book uses @base64-addresses. Ultimately, all @destinations in @I2P are 516-byte (or longer) keys: